Phosphoglyceride crystal deposition disease mimicking a malignant tumor

A 45-year-old woman who had undergone surgical repair for an atrial septal defect at the age of 7 years presented with multiple anterior mediastinal masses. Positron-emission tomography (PET) with 2-[18F]fluoro-2-deoxy-d-glucose (FDG) revealed high uptake in the masses. The findings were interpreted...

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Bibliographic Details
Main Authors: Hiroyuki Tokue, Masayuki Ebara, Ryosuke Takahashi, Azusa Tokue, Yoshito Tsushima
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:European Journal of Radiology Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2352047718300042
Description
Summary:A 45-year-old woman who had undergone surgical repair for an atrial septal defect at the age of 7 years presented with multiple anterior mediastinal masses. Positron-emission tomography (PET) with 2-[18F]fluoro-2-deoxy-d-glucose (FDG) revealed high uptake in the masses. The findings were interpreted as mediastinal malignant tumors with dissemination. Biopsy was performed, and the histological diagnosis was phosphoglyceride crystal deposition disease without neoplastic changes. Although phosphoglyceride crystal deposition disease is rare, it should be recognized as a potential interpretive pitfall that mimics a malignant tumor in FDG-PET findings in a patient after cardiac surgery. Keywords: Phosphoglyceride crystal deposition disease, 2-[18F]Fluoro-2-deoxy-d-glucose (FDG)-Positron-emission tomography (PET)
ISSN:2352-0477