Proteome-scale profiling reveals MAFF and MAFG as two novel key transcription factors involved in palmitic acid-induced umbilical vein endothelial cell apoptosis

Proteome-scale profiling reveals MAFF and MAFG as two novel key transcription factors involved in palmitic acid-induced umbilical vein endothelial cell apoptosis

Abstract Background Vascular endothelial cell apoptosis is the leading risk factor of atherosclerosis (AS). The purpose of our study was to use a new generation high-throughput transcription factor (TF) detection method to identify novel key TFs in vascular endothelial cell apoptosis induced by palm...

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Bibliographic Details
Main Authors: Mangyuan Wang, Fen Liu, Binbin Fang, Qiang Huo, Yining Yang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Cardiovascular Disorders
Subjects:
Apoptosis
Atherosclerosis
Endothelial cell
HUVEC
Palmitic acid
Transcription factor
Online Access:https://doi.org/10.1186/s12872-021-02246-5

Internet

https://doi.org/10.1186/s12872-021-02246-5

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