The use of GA‐RxODE (Genetics Algorithms and Running simulations from Ordinary Differential Equations‐based model) method to optimize bioequivalence studies

The use of GA‐RxODE (Genetics Algorithms and Running simulations from Ordinary Differential Equations‐based model) method to optimize bioequivalence studies

Abstract Bioequivalence (BE) studies are prerequisite in generic products approval. Normally, they are quite simple in design and expensive in execution, and sometimes suffer ethical questioning. Genetics Algorithms and Running simulations from Ordinary Differential Equations‐based model (GA‐RxODE)...

Full description

Bibliographic Details
Main Authors: Ezequiel Omar Nuske, Mikhail Morozov, Héctor Alejandro Serra
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Pharmacology Research & Perspectives
Subjects:
bioequivalence studies
generic drugs
genetics algorithms
NLME models
pharmacokinetic
Online Access:https://doi.org/10.1002/prp2.824

Internet

https://doi.org/10.1002/prp2.824

Similar Items