Ion Channels and Zinc: Mechanisms of Neurotoxicity and Neurodegeneration

Ionotropic glutamate receptors, such as NMDA, AMPA and kainate receptors, are ligand-gated ion channels that mediate much of the excitatory neurotransmission in the brain. Not only do these receptors bind glutamate, but they are also regulated by and facilitate the postsynaptic uptake of the trace m...

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Bibliographic Details
Main Authors: Deborah R. Morris, Cathy W. Levenson
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2012/785647