The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches

The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches

Long non-coding RNAs (lncRNAs) have an undefined role in the pathobiology of glioblastoma multiforme (GBM). These tumors are genetically and phenotypically heterogeneous with transcriptome subtype-specific GBM stem-like cells (GSCs) that adapt to the brain tumor microenvironment, including hypoxic n...

Full description

Bibliographic Details
Main Authors: Marco Mineo, Franz Ricklefs, Arun K. Rooj, Shawn M. Lyons, Pavel Ivanov, Khairul I. Ansari, Ichiro Nakano, E. Antonio Chiocca, Jakub Godlewski, Agnieszka Bronisz
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716305861

Similar Items

Similar Items