Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer.

We validated an 18-gene classifier (GC) initially developed to predict local/regional recurrence after mastectomy in estimating distant metastasis risk. The 18-gene scoring algorithm defines scores as: <21, low risk; ≥21, high risk. Six hundred eighty-three patients with primary operable breast c...

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Bibliographic Details
Main Authors: Skye Hung-Chun Cheng, Tzu-Ting Huang, Yu-Hao Cheng, Tee Benita Kiat Tan, Chen-Fang Horng, Yong Alison Wang, Nicholas Shannon Brian, Li-Sun Shih, Ben-Long Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5590926?pdf=render