The Impact of Metal Ion Exposure on the Cellular Behavior of Human Osteoblasts and PBMCs: In Vitro Analyses of Osteolytic Processes

The Impact of Metal Ion Exposure on the Cellular Behavior of Human Osteoblasts and PBMCs: In Vitro Analyses of Osteolytic Processes

Osteolysis in the periprosthetic tissue can be caused by metallic wear particles and ions that can originate from implant surface corrosion. These products influence cellular behavior and stimulate the expression of proinflammatory cytokines. The purpose of this study was to evaluate the impact of C...

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Bibliographic Details
Main Authors: Anika Jonitz-Heincke, Jenny Tillmann, Annett Klinder, Simone Krueger, Jan Philippe Kretzer, Paul Johan Høl, Alexander C. Paulus, Rainer Bader
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Materials
Subjects:
osteolysis
corrosion
inflammation
osteoblasts
PBMCs
metal ions
CoCr
cytokines
Online Access:https://www.mdpi.com/1996-1944/10/7/734

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