Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling

Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.

Bibliographic Details
Main Authors:	JongOne Im, Sovan Biswas, Hao Liu, Yanan Zhao, Suman Sen, Sudipta Biswas, Brian Ashcroft, Chad Borges, Xu Wang, Stuart Lindsay, Peiming Zhang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-12-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms13868

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spelling	doaj-0abe2c2849774ba6a3d78773e2acb03d2021-05-11T11:12:53ZengNature Publishing GroupNature Communications2041-17232016-12-01711710.1038/ncomms13868Electronic single-molecule identification of carbohydrate isomers by recognition tunnellingJongOne Im0Sovan Biswas1Hao Liu2Yanan Zhao3Suman Sen4Sudipta Biswas5Brian Ashcroft6Chad Borges7Xu Wang8Stuart Lindsay9Peiming Zhang10Biodesign InstituteBiodesign InstituteBiodesign InstituteBiodesign InstituteBiodesign InstituteBiodesign InstituteBiodesign InstituteBiodesign InstituteSchool of Molecular SciencesBiodesign InstituteBiodesign InstituteCarbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.https://doi.org/10.1038/ncomms13868
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	JongOne Im Sovan Biswas Hao Liu Yanan Zhao Suman Sen Sudipta Biswas Brian Ashcroft Chad Borges Xu Wang Stuart Lindsay Peiming Zhang
spellingShingle	JongOne Im Sovan Biswas Hao Liu Yanan Zhao Suman Sen Sudipta Biswas Brian Ashcroft Chad Borges Xu Wang Stuart Lindsay Peiming Zhang Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling Nature Communications
author_facet	JongOne Im Sovan Biswas Hao Liu Yanan Zhao Suman Sen Sudipta Biswas Brian Ashcroft Chad Borges Xu Wang Stuart Lindsay Peiming Zhang
author_sort	JongOne Im
title	Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_short	Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_full	Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_fullStr	Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_full_unstemmed	Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_sort	electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-12-01
description	Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.
url	https://doi.org/10.1038/ncomms13868
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Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling

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