Simultaneous LC-MS/MS-Based Quantification of Free 3-Nitro-l-tyrosine, 3-Chloro-l-tyrosine, and 3-Bromo-l-tyrosine in Plasma of Colorectal Cancer Patients during Early Postoperative Period

Simultaneous LC-MS/MS-Based Quantification of Free 3-Nitro-l-tyrosine, 3-Chloro-l-tyrosine, and 3-Bromo-l-tyrosine in Plasma of Colorectal Cancer Patients during Early Postoperative Period

Quantification with satisfactory specificity and sensitivity of free 3-Nitro-l-tyrosine (3-NT), 3-Chloro-l-tyrosine (3-CT), and 3-Bromo-l-tyrosine (3-BT) in biological samples as potential inflammation, oxidative stress, and cancer biomarkers is analytically challenging. We aimed at developing a liq...

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Bibliographic Details
Main Authors: Mariusz G. Fleszar, Paulina Fortuna, Marek Zawadzki, Bogna Kosyk, Małgorzata Krzystek-Korpacka
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
metabolomics
liquid chromatography–tandem mass spectrometry
oxidative stress
nitrosative stress
inflammation
minimal invasive surgery
Online Access:https://www.mdpi.com/1420-3049/25/21/5158

Internet

https://www.mdpi.com/1420-3049/25/21/5158

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