A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses.

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses.

CD4+ T cell-mediated immunity plays a central role in determining the immunopathogenesis of viral infections. However, the role of CD4+ T cells in EV71 infection, which causes hand, foot and mouth disease (HFMD), has yet to be elucidated. We applied a sophisticated method to identify promiscuous CD4...

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Bibliographic Details
Main Authors: Ruicheng Wei, Chunfu Yang, Mei Zeng, Frances Terry, Kai Zhu, Chunhui Yang, Ralf Altmeyer, William Martin, Anne S De Groot, Qibin Leng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23251663/?tool=EBI

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