Contribution of Immune Cells to Glucocorticoid Receptor Expression in Breast Cancer

Contribution of Immune Cells to Glucocorticoid Receptor Expression in Breast Cancer

Breast cancer (BC) patients experience increased stress with elevated cortisol levels, increasing risk of cancer recurrence. Cortisol binds to a cytoplasmic receptor, glucocorticoid receptor (GR) encoded by GR gene (<i>NR3C1)</i>. We hypothesized that not only cancer cells, but even immu...

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Bibliographic Details
Main Authors: Shipra Gandhi, Ahmed Elkhanany, Masanori Oshi, Tao Dai, Mateusz Opyrchal, Hemn Mohammadpour, Elizabeth A. Repasky, Kazuaki Takabe
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
glucocorticoid receptor
breast cancer
NR3C1
immune cells
TCGA
METABRIC
Online Access:https://www.mdpi.com/1422-0067/21/13/4635

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