Development and validation of a physiology-based model for the prediction of pharmacokinetics/toxicokinetics in rabbits.

The environmental fates of pharmaceuticals and the effects of crop protection products on non-target species are subjects that are undergoing intense review. Since measuring the concentrations and effects of xenobiotics on all affected species under all conceivable scenarios is not feasible, standar...

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Bibliographic Details
Main Authors: Panteleimon D Mavroudis, Helen E Hermes, Donato Teutonico, Thomas G Preuss, Sebastian Schneckener
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5862475?pdf=render