Individualized resuscitation strategy for septic shock formalized by finite mixture modeling and dynamic treatment regimen

Individualized resuscitation strategy for septic shock formalized by finite mixture modeling and dynamic treatment regimen

Abstract Background Septic shock comprises a heterogeneous population, and individualized resuscitation strategy is of vital importance. The study aimed to identify subclasses of septic shock with non-supervised learning algorithms, so as to tailor resuscitation strategy for each class. Methods Pati...

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Bibliographic Details
Main Authors: Penglin Ma, Jingtao Liu, Feng Shen, Xuelian Liao, Ming Xiu, Heling Zhao, Mingyan Zhao, Jing Xie, Peng Wang, Man Huang, Tong Li, Meili Duan, Kejian Qian, Yue Peng, Feihu Zhou, Xin Xin, Xianyao Wan, ZongYu Wang, Shusheng Li, Jianwei Han, Zhenliang Li, Guolei Ding, Qun Deng, Jicheng Zhang, Yue Zhu, Wenjing Ma, Jingwen Wang, Yan Kang, Zhongheng Zhang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Critical Care
Subjects:
Sepsis
Dynamic treatment regime
Mortality
Fluid resuscitation
Online Access:https://doi.org/10.1186/s13054-021-03682-7

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