Intrathecal Grafting of Unencapsulated Adrenal Medullary Tissue can Bring CD4 T Lymphocytes into CSF: A Potentially Deleterious Event for the Graft

Adrenal medullary tissue including chromaffin cells was grafted intrathecally in cancer patients to relieve intractable pain. The central nervous system (CNS) is considered an immune privileged site. Therefore, non-HLA-matched and unencapsulated tissue was grafted in 15 patients and 1 sham control i...

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Bibliographic Details
Main Authors: J. Tkaczuk, J. C. Bes, H. Duplan, B. Sallerin, M. Tafani, J. P. Charlet, M. Abbal, Y. Lazorthes, E. Ohayon
Format: Article
Language:English
Published: SAGE Publishing 2000-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900111