The level of circulating cytokines and chemokines in the preclinical and early clinical stages of development of type 1A diabetes mellitus

Aim: to study the level of circulating proinflammatory (IL-1α, IL-1β, IL-6, α-TNF, IFN-γ) and anti-inflammatory (IL-4, IL-10) cytokines and chemokines (IL-8, IL-16) in preclinical development of type 1A diabetes mellitus (T1DM) in children. Subjects and methods. An examination was made in 450 childr...

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Bibliographic Details
Main Authors: Konstantin Petrovich Zak, Viktoriya Vasil'evna Popova, Svetlana Vitas'kievna Mel'nichenko, Ekaterina Nikolaevna Tron'ko, B N Man'kovskiy, K P Zak, V V Popova, S V Melnichenko, E N Tronko, B N Mankovsky
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2010-10-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30649