An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies

An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies

Developmental and epileptic encephalopathies (DEEs) are complex conditions characterized primarily by seizures associated with neurodevelopmental and motor deficits. Recent evidence supports sigma-1 receptor modulation in both neuroprotection and antiseizure activity, suggesting that sigma-1 recepto...

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Bibliographic Details
Main Authors:	Parthena Martin, Thadd Reeder, Jo Sourbron, Peter A. M. de Witte, Arnold R. Gammaitoni, Bradley S. Galer
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	International Journal of Molecular Sciences
Subjects:	developmental and epileptic encephalopathy fenfluramine sigma-1 receptor serotonin receptor
Online Access:	https://www.mdpi.com/1422-0067/22/16/8416

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