NMR structure of integrin α4 cytosolic tail and its interactions with paxillin.

BACKGROUND: Integrins are a group of transmembrane signaling proteins that are important in biological processes such as cell adhesion, proliferation and migration. Integrins are α/β hetero-dimers and there are 24 different integrins formed by specific combinations of 18 α and 8 β subunits in humans...

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Bibliographic Details
Main Authors: Geok-Lin Chua, Alok Tanala Patra, Suet-Mien Tan, Surajit Bhattacharjya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561355?pdf=render