Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review
Abstract Background Everolimus was recently approved for the treatment of neuroendocrine tumors. However, its efficacy and tolerability in hemodialysis patients with end-stage renal disease is not established. Case presentation We describe the case of a 47-year-old man with end-stage renal disease w...
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| Online Access: | http://link.springer.com/article/10.1186/s12885-018-4205-0 |
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doaj-0a4f212e42a2444c8b56842bc34791932020-11-25T00:44:50ZengBMCBMC Cancer1471-24072018-03-011811310.1186/s12885-018-4205-0Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature reviewM. P. Brizzi0A. La Salvia1M. Tampellini2C. Sonetto3M. Volante4G. V. Scagliotti5Medical Oncology, Department of Oncology, University of Turin, Azienda Ospedaliera Universitaria San LuigiMedical Oncology, Department of Oncology, University of Turin, Azienda Ospedaliera Universitaria San LuigiMedical Oncology, Department of Oncology, University of Turin, Azienda Ospedaliera Universitaria San LuigiMedical Oncology, Department of Oncology, University of Turin, Azienda Ospedaliera Universitaria San LuigiDepartment of Medical Oncology and Pathology, University of Turin, Azienda Ospedaliera Universitaria San LuigiMedical Oncology, Department of Oncology, University of Turin, Azienda Ospedaliera Universitaria San LuigiAbstract Background Everolimus was recently approved for the treatment of neuroendocrine tumors. However, its efficacy and tolerability in hemodialysis patients with end-stage renal disease is not established. Case presentation We describe the case of a 47-year-old man with end-stage renal disease who received everolimus plus Lanreotide for 9 months for the management of metastatic atypical bronchial carcinoid. Conclusions Everolimus is a treatment option for hemodialysis patients with metastatic atypical bronchial carcinoid. Based on our case report and review of literature, Everolimus does not require any dose reductions and is overall well tolerated in hemodialysis patients.http://link.springer.com/article/10.1186/s12885-018-4205-0Bronchial carcinoidsEverolimusHemodialysisPharmacokineticsSafety |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
M. P. Brizzi A. La Salvia M. Tampellini C. Sonetto M. Volante G. V. Scagliotti |
| spellingShingle |
M. P. Brizzi A. La Salvia M. Tampellini C. Sonetto M. Volante G. V. Scagliotti Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review BMC Cancer Bronchial carcinoids Everolimus Hemodialysis Pharmacokinetics Safety |
| author_facet |
M. P. Brizzi A. La Salvia M. Tampellini C. Sonetto M. Volante G. V. Scagliotti |
| author_sort |
M. P. Brizzi |
| title |
Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review |
| title_short |
Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review |
| title_full |
Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review |
| title_fullStr |
Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review |
| title_full_unstemmed |
Efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review |
| title_sort |
efficacy and safety of everolimus treatment in a hemodialysis patient with metastatic atypical bronchial carcinoid: case report and literature review |
| publisher |
BMC |
| series |
BMC Cancer |
| issn |
1471-2407 |
| publishDate |
2018-03-01 |
| description |
Abstract Background Everolimus was recently approved for the treatment of neuroendocrine tumors. However, its efficacy and tolerability in hemodialysis patients with end-stage renal disease is not established. Case presentation We describe the case of a 47-year-old man with end-stage renal disease who received everolimus plus Lanreotide for 9 months for the management of metastatic atypical bronchial carcinoid. Conclusions Everolimus is a treatment option for hemodialysis patients with metastatic atypical bronchial carcinoid. Based on our case report and review of literature, Everolimus does not require any dose reductions and is overall well tolerated in hemodialysis patients. |
| topic |
Bronchial carcinoids Everolimus Hemodialysis Pharmacokinetics Safety |
| url |
http://link.springer.com/article/10.1186/s12885-018-4205-0 |
| work_keys_str_mv |
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