Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction

Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction

Chemical synapses provide a vital foundation for neuron-neuron communication and overall brain function. By tethering closely apposed molecular machinery for presynaptic neurotransmitter release and postsynaptic signal transduction, circuit- and context- specific synaptic properties can drive neuron...

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Bibliographic Details
Main Authors: Motokazu Uchigashima, Amy Cheung, Kensuke Futai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
autism (ASD)
excitatory/inhibitory balance
neuroligin 3 mutation
trans-synaptic adhesion molecule
development
cell adhension molecules
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.749164/full

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