Regulation of spine density and morphology by IQGAP1 protein domains.

Regulation of spine density and morphology by IQGAP1 protein domains.

IQGAP1 is a scaffolding protein that regulates spine number. We now show a differential role for IQGAP1 domains in spine morphogenesis, in which a region of the N-terminus that promotes Arp2/3-mediated actin polymerization and branching stimulates spine head formation while a region that binds to Cd...

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Bibliographic Details
Main Authors: Ignacio Jausoro, Ivan Mestres, Gonzalo Quassollo, Lujan Masseroni, Florencia Heredia, Alfredo Caceres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3575492?pdf=render

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