Label-free morphology-based prediction of multiple differentiation potentials of human mesenchymal stem cells for early evaluation of intact cells.

Precise quantification of cellular potential of stem cells, such as human bone marrow-derived mesenchymal stem cells (hBMSCs), is important for achieving stable and effective outcomes in clinical stem cell therapy. Here, we report a method for image-based prediction of the multiple differentiation p...

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Bibliographic Details
Main Authors: Hiroto Sasaki, Ichiro Takeuchi, Mai Okada, Rumi Sawada, Kei Kanie, Yasujiro Kiyota, Hiroyuki Honda, Ryuji Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3976343?pdf=render