Viral reservoirs in elite controllers of HIV-1 infection: Implications for HIV cure strategies

Elite controllers are HIV-1 positive subjects who control viral replication without antiretroviral therapy. Many of these subjects have replication-competent virus and thus represent a model of a functional cure. Peripheral CD4+ T cells in these subjects have small reservoirs with a low frequency of...

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Bibliographic Details
Main Authors: Bezawit A. Woldemeskel, Abena K. Kwaa, Joel N. Blankson
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:EBioMedicine
Subjects:
HIV
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304941