Infective Larvae of Brugia malayi Induce Polarization of Host Macrophages that Helps in Immune Evasion

Infective Larvae of Brugia malayi Induce Polarization of Host Macrophages that Helps in Immune Evasion

Filarial parasites suppress, divert, or polarize the host immune response to aid their survival. However, mechanisms that govern the polarization of host MΦs during early filarial infection are not completely understood. In this study, we infected BALB/c mice with infective larvae stage-3 of Brugia...

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Bibliographic Details
Main Authors: Aditi Sharma, Pankaj Sharma, Laxmi Ganga, Neha Satoeya, Shikha Mishra, Achchhe Lal Vishwakarma, Mrigank Srivastava
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
filariasis
polarization
M2 MΦ
regulatory MΦ
regulatory T-cell
regulatory B-cell
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00194/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00194/full

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