RNA sequencing and bioinformatics analysis of human lens epithelial cells in age-related cataract

RNA sequencing and bioinformatics analysis of human lens epithelial cells in age-related cataract

Abstract Background Age-related cataract (ARC) is the main cause of blindness in older individuals but its specific pathogenic mechanism is unclear. This study aimed to identify differentially expressed genes (DEGs) associated with ARC and to improve our understanding of the disease mechanism. Metho...

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Bibliographic Details
Main Authors: Zhongying Wang, Dongmei Su, Shanhe Liu, Guiqian Zheng, Gaobo Zhang, Tingsong Cui, Xu Ma, Zhaoyi Sun, Shanshan Hu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Ophthalmology
Subjects:
Age-related cataract
Differentially expressed genes
Bioinformatics analysis
Pathogenic genes
Online Access:https://doi.org/10.1186/s12886-021-01915-5

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