Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography

Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography

Kamil Serkan Agacayak,1 Rıdvan Guler,1 Bekir Ilyasov2 1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakır, Turkey; 2Private Dental Clinic, Diyarbakır, TurkeyCorrespondence: Kamil Serkan AgacayakDepartment of Oral and Maxillofacial Surgery, Faculty of Den...

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Main Authors: Agacayak KS, Guler R, Ilyasov B
Format: Article
Language:English
Published: Dove Medical Press 2019-10-01
Series:Drug Design, Development and Therapy
Subjects:
Antidepressant
bone density
dental tomography.
Online Access:https://www.dovepress.com/evaluation-of-the-effect-of-long-term-use-of-antidepressants-in-the-ss-peer-reviewed-article-DDDT
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spelling doaj-0a028d325a6a4feaaca84c7e252cbe282020-11-24T21:52:59ZengDove Medical PressDrug Design, Development and Therapy1177-88812019-10-01Volume 133477348448937Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomographyAgacayak KSGuler RIlyasov BKamil Serkan Agacayak,1 Rıdvan Guler,1 Bekir Ilyasov2 1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakır, Turkey; 2Private Dental Clinic, Diyarbakır, TurkeyCorrespondence: Kamil Serkan AgacayakDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakir 21280, TurkeyTel +90 412 241 1017Email serkanagacayak@gmail.comAim: The present study aims to employ dental volumetric tomography to examine bone mineral density among men that used antidepressants in the SSRI group for a long time.Method: The present study was conducted through the utilisation of data related to patients that presented to the Faculty of Dentistry of Dicle University and had a dental volumetric tomography (DVT) scan for any reason. The patients were divided into 2 groups based on the use of antidepressants: Group 1 included 68 patients as the control group, and Group 2 consisted of 68 patients that used antidepressants. Radiomorphometric measurements were performed on DVT data: DVT-Mandibular Index (DVT-MI), DVT-Cortical Index (DVT-CI), Hounsfıeld Unit (HU) CORTICAL, and HU SPONGIOSIS values were calculated.Results: The group of patients that used antidepressants exhibited a significant increase in DVT CI and a significant decrease in HU CORTICAL, HU SPONGIOSIS and DVT MI values. These findings were suggestive of osteoporosis.Conclusion: Long-term use of antidepressants should be taken into consideration as a risk factor for osteoporosis in men.Keywords: antidepressant, bone density, dental tomographyhttps://www.dovepress.com/evaluation-of-the-effect-of-long-term-use-of-antidepressants-in-the-ss-peer-reviewed-article-DDDTAntidepressantbone densitydental tomography.
collection DOAJ
language English
format Article
sources DOAJ
author Agacayak KS
Guler R
Ilyasov B
spellingShingle Agacayak KS
Guler R
Ilyasov B
Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography
Drug Design, Development and Therapy
Antidepressant
bone density
dental tomography.
author_facet Agacayak KS
Guler R
Ilyasov B
author_sort Agacayak KS
title Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography
title_short Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography
title_full Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography
title_fullStr Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography
title_full_unstemmed Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography
title_sort evaluation of the effect of long-term use of antidepressants in the ssri group on bone density with dental volumetric tomography
publisher Dove Medical Press
series Drug Design, Development and Therapy
issn 1177-8881
publishDate 2019-10-01
description Kamil Serkan Agacayak,1 Rıdvan Guler,1 Bekir Ilyasov2 1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakır, Turkey; 2Private Dental Clinic, Diyarbakır, TurkeyCorrespondence: Kamil Serkan AgacayakDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakir 21280, TurkeyTel +90 412 241 1017Email serkanagacayak@gmail.comAim: The present study aims to employ dental volumetric tomography to examine bone mineral density among men that used antidepressants in the SSRI group for a long time.Method: The present study was conducted through the utilisation of data related to patients that presented to the Faculty of Dentistry of Dicle University and had a dental volumetric tomography (DVT) scan for any reason. The patients were divided into 2 groups based on the use of antidepressants: Group 1 included 68 patients as the control group, and Group 2 consisted of 68 patients that used antidepressants. Radiomorphometric measurements were performed on DVT data: DVT-Mandibular Index (DVT-MI), DVT-Cortical Index (DVT-CI), Hounsfıeld Unit (HU) CORTICAL, and HU SPONGIOSIS values were calculated.Results: The group of patients that used antidepressants exhibited a significant increase in DVT CI and a significant decrease in HU CORTICAL, HU SPONGIOSIS and DVT MI values. These findings were suggestive of osteoporosis.Conclusion: Long-term use of antidepressants should be taken into consideration as a risk factor for osteoporosis in men.Keywords: antidepressant, bone density, dental tomography
topic Antidepressant
bone density
dental tomography.
url https://www.dovepress.com/evaluation-of-the-effect-of-long-term-use-of-antidepressants-in-the-ss-peer-reviewed-article-DDDT
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