Unknown Areas of Activity of Human Ribonuclease Dicer: A Putative Deoxyribonuclease Activity

Unknown Areas of Activity of Human Ribonuclease Dicer: A Putative Deoxyribonuclease Activity

The Dicer ribonuclease plays a crucial role in the biogenesis of small regulatory RNAs (srRNAs) by processing long double-stranded RNAs and single-stranded hairpin RNA precursors into small interfering RNAs (siRNAs) and microRNAs (miRNAs), respectively. Dicer-generated srRNAs can control gene expres...

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Bibliographic Details
Main Authors: Marta Wojnicka, Agnieszka Szczepanska, Anna Kurzynska-Kokorniak
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
ribonuclease dicer
paz domain
rnase activity
dnase activity
substrate binding pockets
non-canonical dicer substrates
Online Access:https://www.mdpi.com/1420-3049/25/6/1414

Internet

https://www.mdpi.com/1420-3049/25/6/1414

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