Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia.

Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia.

BACKGROUND:Celiac disease (CD) is a systemic immune-mediated disorder developing in HLA genetically predisposed individuals carrying HLA-DQ2 and/or HLA-DQ8 molecules. Recent evidences supported a predominant importance of HLA-DQB1 locus and, in particular, HLA-DQB1*02 alleles. This diagnosis is poor...

Full description

Bibliographic Details
Main Authors: Dimitri Poddighe, Aida Turganbekova, Dana Baymukasheva, Zhazira Saduakas, Zhuldyz Zhanzakova, Saniya Abdrakhmanova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226546

Internet

https://doi.org/10.1371/journal.pone.0226546

Similar Items