The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

<p>Abstract</p> <p>Background</p> <p>A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The...

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Bibliographic Details
Main Authors: Boomkamp Stephanie, Gottwald Ulrich, Leifke Eckhard, Fritsch Martin, Voigtmann Ulrike, Walden Charlotte M, Bone Wilhelm, Platt Frances M, van der Spoel Aarnoud C
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/5/1/1