Utilizing Selected Di- and Trinucleotides of siRNA to Predict RNAi Activity
Small interfering RNAs (siRNAs) induce posttranscriptional gene silencing in various organisms. siRNAs targeted to different positions of the same gene show different effectiveness; hence, predicting siRNA activity is a crucial step. In this paper, we developed and evaluated a powerful tool named “s...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2017-01-01
|
| Series: | Computational and Mathematical Methods in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/5043984 |