Illuminating pathogen-host intimacy through optogenetics.

Illuminating pathogen-host intimacy through optogenetics.

The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience. Here, we introduce selected aspects of optogene...

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Main Authors: Ruben Dario Arroyo-Olarte, Laura Thurow, Vera Kozjak-Pavlovic, Nishith Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007046
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spelling doaj-09caf76c2688400c9f4f495e866392d62021-04-21T17:09:59ZengPublic Library of Science (PLoS)PLoS Pathogens1553-73661553-73742018-07-01147e100704610.1371/journal.ppat.1007046Illuminating pathogen-host intimacy through optogenetics.Ruben Dario Arroyo-OlarteLaura ThurowVera Kozjak-PavlovicNishith GuptaThe birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience. Here, we introduce selected aspects of optogenetics with potential applications in infection biology that will not only answer long-standing questions about intracellular pathogens (parasites, bacteria, viruses) but also broaden the dimension of current research in entwined models. In this essay, we illustrate how a judicious integration of optogenetics with routine methods can illuminate the host-pathogen interactions in a way that has not been feasible otherwise.https://doi.org/10.1371/journal.ppat.1007046
collection DOAJ
language English
format Article
sources DOAJ
author Ruben Dario Arroyo-Olarte
Laura Thurow
Vera Kozjak-Pavlovic
Nishith Gupta
spellingShingle Ruben Dario Arroyo-Olarte
Laura Thurow
Vera Kozjak-Pavlovic
Nishith Gupta
Illuminating pathogen-host intimacy through optogenetics.
PLoS Pathogens
author_facet Ruben Dario Arroyo-Olarte
Laura Thurow
Vera Kozjak-Pavlovic
Nishith Gupta
author_sort Ruben Dario Arroyo-Olarte
title Illuminating pathogen-host intimacy through optogenetics.
title_short Illuminating pathogen-host intimacy through optogenetics.
title_full Illuminating pathogen-host intimacy through optogenetics.
title_fullStr Illuminating pathogen-host intimacy through optogenetics.
title_full_unstemmed Illuminating pathogen-host intimacy through optogenetics.
title_sort illuminating pathogen-host intimacy through optogenetics.
publisher Public Library of Science (PLoS)
series PLoS Pathogens
issn 1553-7366
1553-7374
publishDate 2018-07-01
description The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience. Here, we introduce selected aspects of optogenetics with potential applications in infection biology that will not only answer long-standing questions about intracellular pathogens (parasites, bacteria, viruses) but also broaden the dimension of current research in entwined models. In this essay, we illustrate how a judicious integration of optogenetics with routine methods can illuminate the host-pathogen interactions in a way that has not been feasible otherwise.
url https://doi.org/10.1371/journal.ppat.1007046
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AT laurathurow illuminatingpathogenhostintimacythroughoptogenetics
AT verakozjakpavlovic illuminatingpathogenhostintimacythroughoptogenetics
AT nishithgupta illuminatingpathogenhostintimacythroughoptogenetics
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