Effect of ABCA1 promoter methylation on premature coronary artery disease and its relationship with inflammation

Effect of ABCA1 promoter methylation on premature coronary artery disease and its relationship with inflammation

Abstract Background ATP-binding cassette transporter A1 (ABCA1) plays a major role in high-density lipoprotein (HDL) metabolism and reverse cholesterol transport (RCT) and exerts anti-inflammatory effects. Increased ABCA1 promoter methylation level may result in the progression of coronary artery di...

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Bibliographic Details
Main Authors: Fang An, Chao Liu, Xiujuan Wang, Tan Li, Hao Fu, Buhe Bao, Hongliang Cong, Jihong Zhao
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cardiovascular Disorders
Subjects:
DNA methylation
HDL cholesterol
Coronary artery disease
Neutrophil extracellular traps
ATP-binding cassette transporter
Online Access:https://doi.org/10.1186/s12872-021-01894-x

Internet

https://doi.org/10.1186/s12872-021-01894-x

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