The C677T polymorphism of the methylenetetrahydrofolate reductase gene and susceptibility to late-onset Alzheimer’s disease
Folate metabolism makes a crucial contribution towards late-onset Alzheimer’s disease (LOAD). Moreover, methylenetetrahydrofolate reductase (MTHFR) constitutes the primary enzyme of the folate pathway. We hypothesize that there is an association of C677T polymorphism in the MTHFR gene with the susce...
Main Authors: | Yi Jian, Xiao Lan, Zhou Sheng-Qiang, Zhang Wen-Jiang, Liu Bai-Yan |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2019-01-01
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Series: | Open Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1515/med-2019-0006 |
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