Structural basis of substrate recognition and thermal protection by a small heat shock protein

Structural basis of substrate recognition and thermal protection by a small heat shock protein

Structural insights into the small heat shock proteins (sHsps) complexes with their substrates are sparse. Here, cryo-EM structure of a plastid sHsp, Hsp21, in complex with a bona fide substrate 1-deoxy-D-xylulose 5-phosphate synthase (DXPS), suggests the anti-aggregation mechanism employed by sHsps...

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Bibliographic Details
Main Authors: Chuanyang Yu, Stephen King Pong Leung, Wenxin Zhang, Louis Tung Faat Lai, Ying Ki Chan, Man Chit Wong, Samir Benlekbir, Yong Cui, Liwen Jiang, Wilson Chun Yu Lau
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23338-y

Internet

https://doi.org/10.1038/s41467-021-23338-y

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