Vagus Nerve Stimulation Therapy Randomized to Different Amounts of Electrical Charge for Treatment-Resistant Depression: Acute and Chronic Effects

Vagus Nerve Stimulation Therapy Randomized to Different Amounts of Electrical Charge for Treatment-Resistant Depression: Acute and Chronic Effects

Background: Major depressive disorder is a prevalent, disabling, and often chronic or recurrent psychiatric condition. About 35% of patients fail to respond to conventional treatment approaches and are considered to have treatment-resistant depression (TRD). Objective: We compared the safety and eff...

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Bibliographic Details
Main Authors: Scott T. Aaronson, Linda L. Carpenter, Charles R. Conway, Frederick W. Reimherr, Sarah H. Lisanby, Thomas L. Schwartz, Francisco A. Moreno, David L. Dunner, Michael D. Lesem, Peter M. Thompson, Mustafa Husain, Craig J. Vine, Michael D. Banov, Lawrence P. Bernstein, Robert B. Lehman, Guy E. Brannon, George A. Keepers, John P. O'Reardon, Richard L. Rudolph, Mark Bunker
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Brain Stimulation
Subjects:
Dose response
Treatment durability
Treatment-resistant depression
VNS efficacy
Vagus nerve stimulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X1200188X

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