Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana

Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana

Ammonium is an important nitrogen source for plants but excess ammonium impairs growth. Here the authors show that ammonium toxicity results from assimilation by GLUTAMINE SYNTHETASE 2 in the plastids which results in excess proton accumulation and acidity stress.

Bibliographic Details
Main Authors: Takushi Hachiya, Jun Inaba, Mayumi Wakazaki, Mayuko Sato, Kiminori Toyooka, Atsuko Miyagi, Maki Kawai-Yamada, Daisuke Sugiura, Tsuyoshi Nakagawa, Takatoshi Kiba, Alain Gojon, Hitoshi Sakakibara
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25238-7
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spelling doaj-09b2ececf8664e8788f5d73145f04ece2021-08-22T11:39:20ZengNature Publishing GroupNature Communications2041-17232021-08-0112111010.1038/s41467-021-25238-7Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thalianaTakushi Hachiya0Jun Inaba1Mayumi Wakazaki2Mayuko Sato3Kiminori Toyooka4Atsuko Miyagi5Maki Kawai-Yamada6Daisuke Sugiura7Tsuyoshi Nakagawa8Takatoshi Kiba9Alain Gojon10Hitoshi Sakakibara11Department of Molecular and Functional Genomics, Interdisciplinary Center for Science Research, Shimane UniversityRIKEN Center for Sustainable Resource ScienceRIKEN Center for Sustainable Resource ScienceRIKEN Center for Sustainable Resource ScienceRIKEN Center for Sustainable Resource ScienceGraduate School of Science and Engineering, Saitama UniversityGraduate School of Science and Engineering, Saitama UniversityGraduate School of Bioagricultural Sciences, Nagoya UniversityDepartment of Molecular and Functional Genomics, Interdisciplinary Center for Science Research, Shimane UniversityGraduate School of Bioagricultural Sciences, Nagoya UniversityBiochimie et Physiologie Moléculaire des Plantes, CNRS/INRA/SupAgro-M/Montpellier UniversityGraduate School of Bioagricultural Sciences, Nagoya UniversityAmmonium is an important nitrogen source for plants but excess ammonium impairs growth. Here the authors show that ammonium toxicity results from assimilation by GLUTAMINE SYNTHETASE 2 in the plastids which results in excess proton accumulation and acidity stress.https://doi.org/10.1038/s41467-021-25238-7
collection DOAJ
language English
format Article
sources DOAJ
author Takushi Hachiya
Jun Inaba
Mayumi Wakazaki
Mayuko Sato
Kiminori Toyooka
Atsuko Miyagi
Maki Kawai-Yamada
Daisuke Sugiura
Tsuyoshi Nakagawa
Takatoshi Kiba
Alain Gojon
Hitoshi Sakakibara
spellingShingle Takushi Hachiya
Jun Inaba
Mayumi Wakazaki
Mayuko Sato
Kiminori Toyooka
Atsuko Miyagi
Maki Kawai-Yamada
Daisuke Sugiura
Tsuyoshi Nakagawa
Takatoshi Kiba
Alain Gojon
Hitoshi Sakakibara
Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana
Nature Communications
author_facet Takushi Hachiya
Jun Inaba
Mayumi Wakazaki
Mayuko Sato
Kiminori Toyooka
Atsuko Miyagi
Maki Kawai-Yamada
Daisuke Sugiura
Tsuyoshi Nakagawa
Takatoshi Kiba
Alain Gojon
Hitoshi Sakakibara
author_sort Takushi Hachiya
title Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana
title_short Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana
title_full Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana
title_fullStr Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana
title_full_unstemmed Excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in Arabidopsis thaliana
title_sort excessive ammonium assimilation by plastidic glutamine synthetase causes ammonium toxicity in arabidopsis thaliana
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-08-01
description Ammonium is an important nitrogen source for plants but excess ammonium impairs growth. Here the authors show that ammonium toxicity results from assimilation by GLUTAMINE SYNTHETASE 2 in the plastids which results in excess proton accumulation and acidity stress.
url https://doi.org/10.1038/s41467-021-25238-7
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