The Relationship Between Environmental Exposure and Genetic Architecture of the 2q33 Locus With Esophageal Cancer in South Africa

The Relationship Between Environmental Exposure and Genetic Architecture of the 2q33 Locus With Esophageal Cancer in South Africa

Esophageal squamous cell carcinoma (ESCC) has a high prevalence in several countries in Africa and Asia. Previous genome-wide association studies (GWAS) in Chinese populations have identified several ESCC susceptibility loci, including variants on chromosome 2q33 and 6p21, but the contribution of th...

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Bibliographic Details
Main Authors:	Marco Matejcic, Christopher G. Mathew, M. Iqbal Parker
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-05-01
Series:	Frontiers in Genetics
Subjects:	genetic association single nucleotide polymorphism esophageal squamous cell carcinoma South African populations major histocompatibility complex 2q33
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2019.00406/full

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