Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis.

Aging-associated alterations of cellular functions have been implicated in various disorders including cancers. Due to difficulties in identifying aging cells in living tissues, most studies have focused on aging-associated changes in whole tissues or certain cell pools. Thus, it remains unclear wha...

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Bibliographic Details
Main Authors: Yoshihisa Okuchi, Masamichi Imajo, Rei Mizuno, Yuji Kamioka, Hiroyuki Miyoshi, Makoto Mark Taketo, Satoshi Nagayama, Yoshiharu Sakai, Michiyuki Matsuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5010213?pdf=render