Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells

Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells

The double membrane nuclear envelope (NE), which is contiguous with the ER, contains nuclear pore complexes (NPCs) – the channels for nucleocytoplasmic transport, and the nuclear lamina (NL) – a scaffold for NE and chromatin organization. Since numerous human diseases linked to NE proteins occur in...

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Bibliographic Details
Main Authors: Li-Chun Cheng, Sabyasachi Baboo, Cory Lindsay, Liza Brusman, Salvador Martinez-Bartolomé, Olga Tapia, Xi Zhang, John R. Yates, Larry Gerace
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Nucleus
Subjects:
nuclear envelope
nuclear pore complex (npc)
proteomics
mesenchymal stem cell (msc)
adipocyte
myocyte
Online Access:http://dx.doi.org/10.1080/19491034.2019.1618175

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