The cancer stem cell marker CD133 interacts with plakoglobin and controls desmoglein-2 protein levels.

The cancer stem cell marker CD133 interacts with plakoglobin and controls desmoglein-2 protein levels.

The pentaspan membrane glycoprotein CD133 (also known as prominin-1) has been widely used as a marker for both cancer and normal stem cells. However, the function of CD133 has not been elucidated. Here we describe a cancer stem cell line established from clear cell carcinoma of the ovary (CCC) and s...

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Bibliographic Details
Main Authors: Ryo Koyama-Nasu, Rina Takahashi, Satoshi Yanagida, Yukiko Nasu-Nishimura, Masaaki Oyama, Hiroko Kozuka-Hata, Ryo Haruta, Emi Manabe, Akemi Hoshino-Okubo, Hiroko Omi, Nozomu Yanaihara, Aikou Okamoto, Tadao Tanaka, Tetsu Akiyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3542344?pdf=render

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