Rhesus Brain Transcriptomic Landscape in an ex vivo Model of the Interaction of Live Borrelia Burgdorferi With Frontal Cortex Tissue Explants

Rhesus Brain Transcriptomic Landscape in an ex vivo Model of the Interaction of Live Borrelia Burgdorferi With Frontal Cortex Tissue Explants

Lyme neuroborreliosis (LNB) is the most dangerous manifestation of Lyme disease caused by the spirochete Borrelia burgdorferi which can reach the central nervous system most commonly presenting with lymphocytic meningitis; however, the molecular basis for neuroborreliosis is still poorly understood....

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Bibliographic Details
Main Authors: Zhe Ding, Mingbiao Ma, Lvyan Tao, Yun Peng, Yuanyuan Han, Luyun Sun, Xiting Dai, Zhenhua Ji, Ruolan Bai, Miaomiao Jian, Taigui Chen, Lisha Luo, Feng Wang, Yunfeng Bi, Aihua Liu, Fukai Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
Subjects:
transcriptomic analysis
innate immune system
neuroinflammation
CNS
Borrelia burgdorferi
Lyme neuroborreliosis
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00651/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00651/full

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