Chylomicron remnant uptake is regulated by the expression and function of heparan sulfate proteoglycan in hepatocytes

Chylomicron remnant uptake is regulated by the expression and function of heparan sulfate proteoglycan in hepatocytes

Chylomicron remnants transport cholesterol from the intestine, and are removed from the circulation principally by the liver. While hepatic receptors, including the low density lipoprotein (LDL) receptor account for endocytosis, heparan sulfate proteoglycans (HSPG) participate in the initial binding...

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Bibliographic Details
Main Authors: Bing-Ji Zeng, Bok-Cheng Mortimer, Ian J. Martins, Ulrich Seydel, Trevor G. Redgrave
Format: Article
Language:English
Published: Elsevier 1998-04-01
Series:Journal of Lipid Research
Subjects:
antisense
antibody
competitor
inhibitor
receptor
blocker
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520325712

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