Chylomicron remnant uptake is regulated by the expression and function of heparan sulfate proteoglycan in hepatocytes
Chylomicron remnants transport cholesterol from the intestine, and are removed from the circulation principally by the liver. While hepatic receptors, including the low density lipoprotein (LDL) receptor account for endocytosis, heparan sulfate proteoglycans (HSPG) participate in the initial binding...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1998-04-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520325712 |