Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions

SARS-CoV-2-antigen-testing has been proposed as a ‘game-changing’ tool to interrupt infection chains. Thereby European strategies focused on two pillars, namely rapid antigen tests conducted by health care experts and/or trained personal and so-called self-tests. Here, evidence is provided that thes...

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Main Authors: S. Demuth, S. Damaschek, O. Schildgen, V. Schildgen
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:New Microbes and New Infections
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297521000809
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spelling doaj-098520fea4a34b97921248d9172fa7f32021-10-01T04:56:26ZengElsevierNew Microbes and New Infections2052-29752021-09-0143100916Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditionsS. Demuth0S. Damaschek1O. Schildgen2V. Schildgen3Kliniken der Stadt Köln, Institut für Pathologie, Klinikum der Privaten Universität Witten Herdecke mit Sitz in Köln, Ostmerheimer Str. 200, D-51109, Cologne, GermanyKliniken der Stadt Köln, Institut für Pathologie, Klinikum der Privaten Universität Witten Herdecke mit Sitz in Köln, Ostmerheimer Str. 200, D-51109, Cologne, GermanyCorresponding author: O. Schildgen, Dipl.-Biologe, Fachvirologe GfV Kliniken der Stadt Köln gGmbH Klinikum der Privaten Universität Witten/Herdecke Institut für Pathologie, Ostmerheimer Str. 200, D-51109, Köln (Cologne), Germany; Kliniken der Stadt Köln, Institut für Pathologie, Klinikum der Privaten Universität Witten Herdecke mit Sitz in Köln, Ostmerheimer Str. 200, D-51109, Cologne, GermanyKliniken der Stadt Köln, Institut für Pathologie, Klinikum der Privaten Universität Witten Herdecke mit Sitz in Köln, Ostmerheimer Str. 200, D-51109, Cologne, GermanySARS-CoV-2-antigen-testing has been proposed as a ‘game-changing’ tool to interrupt infection chains. Thereby European strategies focused on two pillars, namely rapid antigen tests conducted by health care experts and/or trained personal and so-called self-tests. Here, evidence is provided that these assays have a weak performance even under laboratory conditions.http://www.sciencedirect.com/science/article/pii/S2052297521000809Rapid antigen assaysSARS-CoV-2self-testing
collection DOAJ
language English
format Article
sources DOAJ
author S. Demuth
S. Damaschek
O. Schildgen
V. Schildgen
spellingShingle S. Demuth
S. Damaschek
O. Schildgen
V. Schildgen
Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions
New Microbes and New Infections
Rapid antigen assays
SARS-CoV-2
self-testing
author_facet S. Demuth
S. Damaschek
O. Schildgen
V. Schildgen
author_sort S. Demuth
title Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions
title_short Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions
title_full Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions
title_fullStr Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions
title_full_unstemmed Low sensitivity of SARS-CoV-2 rapid antigen self-tests under laboratory conditions
title_sort low sensitivity of sars-cov-2 rapid antigen self-tests under laboratory conditions
publisher Elsevier
series New Microbes and New Infections
issn 2052-2975
publishDate 2021-09-01
description SARS-CoV-2-antigen-testing has been proposed as a ‘game-changing’ tool to interrupt infection chains. Thereby European strategies focused on two pillars, namely rapid antigen tests conducted by health care experts and/or trained personal and so-called self-tests. Here, evidence is provided that these assays have a weak performance even under laboratory conditions.
topic Rapid antigen assays
SARS-CoV-2
self-testing
url http://www.sciencedirect.com/science/article/pii/S2052297521000809
work_keys_str_mv AT sdemuth lowsensitivityofsarscov2rapidantigenselftestsunderlaboratoryconditions
AT sdamaschek lowsensitivityofsarscov2rapidantigenselftestsunderlaboratoryconditions
AT oschildgen lowsensitivityofsarscov2rapidantigenselftestsunderlaboratoryconditions
AT vschildgen lowsensitivityofsarscov2rapidantigenselftestsunderlaboratoryconditions
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