Melatonin selectively influences the transcription of pluripotency and differentiation markers in human non-cancer cells

Melatonin selectively influences the transcription of pluripotency and differentiation markers in human non-cancer cells

Melatonin (MEL) may influence the efficiency of reprogramming both by somatic cell nuclear transfer and by direct induction of pluripotent stem cells (iPSC) through a yet unidentified mechanism. Transcription factors linked to cell reprogramming and cell signalling may be differentially expressed ac...

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Bibliographic Details
Main Authors: Georgi Nikolaev Georgiev, Elena Marinova, Rossitza Konakchieva, Plamen Todorov
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
melatonin
mt1
erk1/2
klf4
c-myc
nanog
Online Access:http://dx.doi.org/10.1080/13102818.2019.1571440

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