Experimental Evolution of Campylobacter jejuni Leads to Loss of Motility, rpoN (σ54) Deletion and Genome Reduction

Experimental Evolution of Campylobacter jejuni Leads to Loss of Motility, rpoN (σ54) Deletion and Genome Reduction

Evolution experiments in the laboratory have focused heavily on model organisms, often to the exclusion of clinically relevant pathogens. The foodborne bacterial pathogen Campylobacter jejuni belongs to a genus whose genomes are small compared to those of its closest genomic relative, the free-livin...

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Bibliographic Details
Main Authors: Azam A. Sher, John P. Jerome, Julia A. Bell, Julian Yu, Hahyung Y. Kim, Jeffrey E. Barrick, Linda S. Mansfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
Campylobacter jejuni
laboratory evolution
phase variation
motility
RpoN
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.579989/full

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