The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development.

The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development.

Rhodococcus equi causes fatal pyogranulomatous pneumonia in foals and immunocompromised animals and humans. Despite its importance, there is currently no effective vaccine against the disease. The actinobacteria R. equi and the human pathogen Mycobacterium tuberculosis are related, and both cause pu...

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Bibliographic Details
Main Authors: R van der Geize, A W F Grommen, G I Hessels, A A C Jacobs, L Dijkhuizen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3161971?pdf=render

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