Will Lipidation of ApoA1 through Interaction with ABCA1 at the Intestinal Level Affect the Protective Functions of HDL?
The relationship between levels of high-density lipoprotein cholesterol (HDL-C) and cardiovascular (CV) risk is well recognized; however, in recent years, large-scale phase III studies with HDL-C-raising or -mimicking agents have failed to demonstrate a clinical benefit on CV outcomes associated wit...
Main Author: | Eric J. Niesor |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-01-01
|
Series: | Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-7737/4/1/17 |
Similar Items
-
Régulation moléculaire et cellulaire de l'efflux de cholestérol par le transporteur ATP-binding cassette A1(ABCA1)
by: Denis, Maxime
Published: (2016) -
ApoA-I secretion from HepG2 cells: evidence for the secretion of both lipid-poor apoA-I and intracellularly assembled nascent HDL
by: Jeffrey W. Chisholm, et al.
Published: (2002-01-01) -
Biogénèse des lipoprotéines de haute densité (HDL): implication du transporteur ABCA1
by: Hajj Hassan, Houssein
Published: (2011) -
Biogénèse des lipoprotéines de haute densité (HDL): implication du transporteur ABCA1
by: Hajj Hassan, Houssein
Published: (2011) -
ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding[S]
by: Kohjiro Nagao, et al.
Published: (2012-01-01)