Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect

Abstract Background This study investigated the mechanisms underlying the preventive effect of dihydromyricetin (DHM) against liver fibrosis involving hepatic stellate cells (HSCs) and hepatic natural killer (NK) cells. Methods A carbon tetrachloride (CCl4)-induced liver fibrosis model was establish...

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Bibliographic Details
Main Authors: Xi Zhou, Li Yu, Min Zhou, Pengfei Hou, Long Yi, Mantian Mi
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Nutrition & Metabolism
Subjects:
Online Access:https://doi.org/10.1186/s12986-021-00589-6