Monocarboxylate Transporters and Lactate Metabolism in Equine Athletes: A Review
<p/> <p>Lactate is known as the end product of anaerobic glycolysis, a pathway that is of key importance during high intensity exercise. Instead of being a waste product lactate is now regarded as a valuable substrate that significantly contributes to the energy production of heart, nonc...
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| Format: | Article |
| Language: | English |
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BMC
2002-06-01
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| Series: | Acta Veterinaria Scandinavica |
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| Online Access: | http://www.actavetscand.com/content/43/2/63 |
| Summary: | <p/> <p>Lactate is known as the end product of anaerobic glycolysis, a pathway that is of key importance during high intensity exercise. Instead of being a waste product lactate is now regarded as a valuable substrate that significantly contributes to the energy production of heart, noncontracting muscles and even brain. The recent cloning of monocarboxylate transporters, a conserved protein family that transports lactate through biological membranes, has given a new insight into the role of lactate in whole body metabolism. This paper reviews current literature on lactate and monocarboxylate transporters with special reference to horses.</p> |
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| ISSN: | 1751-0147 |