Ethanol modulation of mammalian BK channels in excitable tissues: molecular targets and their possible contribution to alcohol-induced altered behavior

Ethanol modulation of mammalian BK channels in excitable tissues: molecular targets and their possible contribution to alcohol-induced altered behavior

In most tissues, the function of calcium- and voltage-gated potassium (BK) channels is modified in response to ethanol concentrations reached in human blood during alcohol intoxication. In general, modification of BK current from ethanol-naïve preparations in response to brief ethanol exposure resu...

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Bibliographic Details
Main Authors: Alex M. Dopico, Anna eBukiya, Gilles eMartin
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Physiology
Subjects:
Ion Channels
Membrane Lipids
n-Alkanols
Alcohol tolerance
slo1 proteins
BK beta subunits
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00466/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00466/full

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